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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-6-16
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pubmed:abstractText |
Vasculopathy is one of the hallmarks of systemic sclerosis (SSc), characterized by endothelial activation and over expression of adhesion molecules. A preliminary in vitro study has suggested that aminaftone, a naphtohydrochinone used in the treatment of capillary disorders, may downregulate the expression of adhesion molecules in endothelial cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0149-2918
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
924-9
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pubmed:meshHeading |
pubmed-meshheading:18555939-4-Aminobenzoic Acid,
pubmed-meshheading:18555939-Cell Adhesion Molecules,
pubmed-meshheading:18555939-E-Selectin,
pubmed-meshheading:18555939-Female,
pubmed-meshheading:18555939-Humans,
pubmed-meshheading:18555939-Intercellular Adhesion Molecule-1,
pubmed-meshheading:18555939-Male,
pubmed-meshheading:18555939-Middle Aged,
pubmed-meshheading:18555939-Pilot Projects,
pubmed-meshheading:18555939-Prospective Studies,
pubmed-meshheading:18555939-Scleroderma, Systemic,
pubmed-meshheading:18555939-Solubility,
pubmed-meshheading:18555939-Vascular Cell Adhesion Molecule-1
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pubmed:year |
2008
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pubmed:articleTitle |
Effects of aminaftone 75 mg TID on soluble adhesion molecules: a 12-week, randomized, open-label pilot study in patients with systemic sclerosis.
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pubmed:affiliation |
Referral Center for Systemic Autoimmune Diseases, University of Milan, Milan, Italy. raffaella.scorza@unimi.it
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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