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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-8-29
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pubmed:abstractText |
63 patients with hypocitraturia (44.9% of the total) and 33 patients with hypomagnesiuria (24.8% of the total) received oral magnesium hydroxide and/or Na/K citrate in addition to other therapeutic agents if indicated and a common-sense diet. Hypocitraturic patients were categorized into 3 groups and received 27-81 mEq/day oral citrate according to the deficiency grade. Hypomagnesiuric patients also formed two groups according to the deficiency grade and received 500 and 1,000 mg/day magnesium hydroxide, respectively. Replacement was intermittant and was controlled every 3 months until reaching normal values. We evaluated 28 of 63 hypocitraturic and 15 of 33 hypomagnesiuric patients who had inhibitory deficiency as the sole causal factor of their urolithiasis. After a follow-up of 13.5 +/- 10.2 months, no patient in either group developed a new stone. Citrate and magnesium were increased significantly in the respective groups; calcium and oxalate excretion was lowered, and urine pH and volume increased significantly. A deficiency grade-adjusted and intermittant replacement therapy with Mg and citrate is very effective, has less side effects and ensures good patients compliance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0302-2838
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
244-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1855531-Adult,
pubmed-meshheading:1855531-Citrates,
pubmed-meshheading:1855531-Citric Acid,
pubmed-meshheading:1855531-Female,
pubmed-meshheading:1855531-Follow-Up Studies,
pubmed-meshheading:1855531-Humans,
pubmed-meshheading:1855531-Magnesium,
pubmed-meshheading:1855531-Magnesium Hydroxide,
pubmed-meshheading:1855531-Male,
pubmed-meshheading:1855531-Time Factors,
pubmed-meshheading:1855531-Urinary Calculi
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pubmed:year |
1991
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pubmed:articleTitle |
Role of inhibitor deficiency in urolithiasis. II. Deficiency grade-adjusted and intermittent augmentation therapy for magnesium and citrate deficiency.
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pubmed:affiliation |
Department of Urology, Medical Faculty of Instanbul, Turkey.
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pubmed:publicationType |
Journal Article
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