|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006050,
umls-concept:C0006931,
umls-concept:C0017262,
umls-concept:C0026336,
umls-concept:C0033581,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0240812,
umls-concept:C0387583,
umls-concept:C1512969,
umls-concept:C1533685,
umls-concept:C1637391,
umls-concept:C2911684
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2008-7-14
|
|
pubmed:abstractText |
Cyclooxygenase-2 is a key enzyme in the conversion of arachidonic acid to prostaglandins, which are important mediators of inflammation and pain. We investigated the effect of intraprostatic botulinum toxin A administration on pain reaction and cyclooxygenase-2 expression in a capsaicin induced prostatitis model in rats.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1527-3792
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
180
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
742-8
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:18554636-Animals,
pubmed-meshheading:18554636-Botulinum Toxins, Type A,
pubmed-meshheading:18554636-Capsaicin,
pubmed-meshheading:18554636-Cyclooxygenase 2,
pubmed-meshheading:18554636-Disease Models, Animal,
pubmed-meshheading:18554636-Dose-Response Relationship, Drug,
pubmed-meshheading:18554636-Immunohistochemistry,
pubmed-meshheading:18554636-Inflammation Mediators,
pubmed-meshheading:18554636-Injections, Intralesional,
pubmed-meshheading:18554636-Lumbar Vertebrae,
pubmed-meshheading:18554636-Male,
pubmed-meshheading:18554636-Pain,
pubmed-meshheading:18554636-Pain Measurement,
pubmed-meshheading:18554636-Probability,
pubmed-meshheading:18554636-Prostatitis,
pubmed-meshheading:18554636-Random Allocation,
pubmed-meshheading:18554636-Rats,
pubmed-meshheading:18554636-Rats, Sprague-Dawley,
pubmed-meshheading:18554636-Reference Values,
pubmed-meshheading:18554636-Sensitivity and Specificity,
pubmed-meshheading:18554636-Spinal Cord
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Intraprostatic botulinum toxin a injection inhibits cyclooxygenase-2 expression and suppresses prostatic pain on capsaicin induced prostatitis model in rat.
|
|
pubmed:affiliation |
Department of Urology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China. chuang82@ms26.hinet.net
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
