rdf:type |
|
lifeskim:mentions |
umls-concept:C0006675,
umls-concept:C0006772,
umls-concept:C0017262,
umls-concept:C0034693,
umls-concept:C0185117,
umls-concept:C0205191,
umls-concept:C0225828,
umls-concept:C0242184,
umls-concept:C0248868,
umls-concept:C0441655,
umls-concept:C1280500,
umls-concept:C2911684
|
pubmed:issue |
3
|
pubmed:dateCreated |
2008-6-16
|
pubmed:abstractText |
Calcium plays an important role in the impairment of heart function and arrhythmia under the condition of acute hypoxia, but the mechanism is different from that of chronic hypoxia. This study aimed to evaluate the effect of chronic hypoxia on the expression of calmodulin (CaM) and calcicum/calmodulin-dependent protein kinase II (CaMKII) and the calcium activity in myocardial cells through an animal model of chronic hypoxia in order to get a deeper sight into the mechanism.
|
pubmed:language |
chi
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1008-8830
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
381-5
|
pubmed:meshHeading |
pubmed-meshheading:18554473-1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine,
pubmed-meshheading:18554473-Animals,
pubmed-meshheading:18554473-Anoxia,
pubmed-meshheading:18554473-Blotting, Western,
pubmed-meshheading:18554473-Calcium,
pubmed-meshheading:18554473-Calcium-Calmodulin-Dependent Protein Kinase Type 2,
pubmed-meshheading:18554473-Calmodulin,
pubmed-meshheading:18554473-Chronic Disease,
pubmed-meshheading:18554473-Male,
pubmed-meshheading:18554473-Myocardium,
pubmed-meshheading:18554473-Norepinephrine,
pubmed-meshheading:18554473-Rats,
pubmed-meshheading:18554473-Rats, Sprague-Dawley,
pubmed-meshheading:18554473-Reverse Transcriptase Polymerase Chain Reaction
|
pubmed:year |
2008
|
pubmed:articleTitle |
[Effects of chronic hypoxia on the expression of calmodulin and calcicum/calmodulin-dependent protein kinase II and the calcium activity in myocardial cells in young rats].
|
pubmed:affiliation |
Shanghai Children's Medical Center, Shanghai Jiao Tong University, Shanghai 200127, China. pjunzhao@sina.com
|
pubmed:publicationType |
Journal Article,
English Abstract
|