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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-10-27
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pubmed:abstractText |
Moderate hyperhomocysteinemia is a known risk factor for NTDs in a variety of experimental model systems and is believed to be important in humans as well. The enzyme nicotinamide N-methyl transferase (NNMT) was identified in a genome-wide linkage scan as being an important regulator of homocysteine homeostasis in a Spanish population, making it an interesting candidate gene for NTDs.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1542-0760
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2008 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
670-5
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pubmed:dateRevised |
2011-6-14
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pubmed:meshHeading |
pubmed-meshheading:18553462-Alleles,
pubmed-meshheading:18553462-Case-Control Studies,
pubmed-meshheading:18553462-Genotype,
pubmed-meshheading:18553462-Haplotypes,
pubmed-meshheading:18553462-Humans,
pubmed-meshheading:18553462-Infant,
pubmed-meshheading:18553462-Nicotinamide N-Methyltransferase,
pubmed-meshheading:18553462-Polymorphism, Single Nucleotide,
pubmed-meshheading:18553462-Risk Factors,
pubmed-meshheading:18553462-Sequence Analysis, DNA,
pubmed-meshheading:18553462-Spinal Dysraphism
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pubmed:year |
2008
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pubmed:articleTitle |
Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida.
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pubmed:affiliation |
Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, N.I.H., Extramural
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