|
pubmed:abstractText |
Perturbations in energetic metabolism and impaired atrial contractility may play an important role in the pathogenesis of atrial fibrillation (AF). Besides, atrial stretch is commonly associated with AF. However, the atrial energetics of stretch-related AF are poorly understood. Here, we measured indicators of energy metabolism during acute stretch-related AF. PCr, adenine nucleotides, and derivatives concentrations as well as the activity of the F(0)F(1)-ATPase and Na,K-ATPase were obtained after 1 h of stretch and/or AF in isolated rabbit hearts and compared to control hearts without stretch and AF.
|
|
pubmed:affiliation |
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), CNRS UMR n degrees 6612, Faculté de Médecine de Marseille, Université de la Méditerranée, 27 Bd Jean Moulin, 13385, Marseille Cedex 5, France.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
