Linked Life Data

1855146

Source:http://linkedlifedata.com/resource/pubmed/id/1855146

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-8-23
pubmed:abstractText
Angiotensin II (AII) receptor subtypes have been proposed on the basis of the selectivity of non-peptide AII antagonists. In the present study, the sulfhydryl reducing agent dithiothreitol (DTT) was found to reduce binding to the AII-1 receptor while enhancing binding at the AII-2 site. The neuroanatomical distribution of these effects were consistent with the distribution of AII-1 and AII-2 receptors, respectively. These data indicate that AII receptor subtypes in the brain can be differentiated by both biochemical and pharmacological means.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
546
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
161-5
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Angiotensin II receptor subtypes in rat brain: dithiothreitol inhibits ligand binding to AII-1 and enhances binding to AII-2.
pubmed:affiliation
Central Nervous System Research, Eli Lilly and Company, Indianapolis, IN 46285.
pubmed:publicationType
Journal Article, In Vitro