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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0002708,
umls-concept:C0028351,
umls-concept:C0030685,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0038435,
umls-concept:C0205217,
umls-concept:C0206056,
umls-concept:C0391871,
umls-concept:C0442111,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1963578,
umls-concept:C2603343
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pubmed:issue |
1
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pubmed:dateCreated |
1991-8-29
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pubmed:abstractText |
The effects of immobilization and tail-pinch stress on extracellular noradrenaline (NA) release in the amygdala were studied in freely moving rats with intracerebral microdialysis techniques. After collection of basal levels of NA (2.63 +/- 0.26 pg/50 microliters/20 min), the rat was exposed to either immobilization stress or tail-pinch stress for 20 min. Immobilization and tail-pinch stress increased NA release to 250 and 243% of basal levels, respectively and the elevation of NA release was observed for 60 min and 40 min after release from stress, also respectively. These data suggest that microdialysis is a useful way to study extracellular NA release in the amygdala and that NA neurons in this region are activated by both immobilization and tail-pinch stress.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
544
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
174-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1855137-Amygdala,
pubmed-meshheading:1855137-Animals,
pubmed-meshheading:1855137-Dialysis,
pubmed-meshheading:1855137-Kinetics,
pubmed-meshheading:1855137-Male,
pubmed-meshheading:1855137-Norepinephrine,
pubmed-meshheading:1855137-Pain,
pubmed-meshheading:1855137-Rats,
pubmed-meshheading:1855137-Rats, Inbred Strains,
pubmed-meshheading:1855137-Restraint, Physical,
pubmed-meshheading:1855137-Stress, Psychological
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pubmed:year |
1991
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pubmed:articleTitle |
Noradrenaline release in the rat amygdala is increased by stress: studies with intracerebral microdialysis.
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pubmed:affiliation |
Department of Pharmacology, Kurume University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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