18549897

Source:http://linkedlifedata.com/resource/pubmed/id/18549897

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017262, umls-concept:C0069676, umls-concept:C0185117, umls-concept:C0443199, umls-concept:C0752249, umls-concept:C0851285, umls-concept:C1881800, umls-concept:C2239176, umls-concept:C2911684
pubmed:issue	6
pubmed:dateCreated	2008-6-13
pubmed:abstractText	Osteopontin (OPN) is a potential therapeutic target in hepatocellular carcinoma (HCC), because it is a critical mediator of metastatic function. The molecular mechanisms that determine expression of OPN in HCC, however, are unknown. In this study, we examine differential OPN expression in the 2 HCC cell lines: HepG2 and Hep3B.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AI44629, http://linkedlifedata.com/resource/pubmed/grant/DK070642, http://linkedlifedata.com/resource/pubmed/grant/GM65113, http://linkedlifedata.com/resource/pubmed/grant/R01 AI044629-07, http://linkedlifedata.com/resource/pubmed/grant/R01 GM065113-04
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0417347
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/5' Untranslated Regions, http://linkedlifedata.com/resource/pubmed/chemical/Osteopontin, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1532-7361
pubmed:author	pubmed-author:EmaniSirishaS, pubmed-author:GuoHongtaoH, pubmed-author:GuoLucieL, pubmed-author:KuoPaul CPC, pubmed-author:ZhangJinpingJ
pubmed:issnType	Electronic
pubmed:volume	143
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	803-12
pubmed:dateRevised	2011-8-1
pubmed:meshHeading	pubmed-meshheading:18549897-5' Untranslated Regions, pubmed-meshheading:18549897-Carcinoma, Hepatocellular, pubmed-meshheading:18549897-Cell Line, Tumor, pubmed-meshheading:18549897-Gene Expression Regulation, Neoplastic, pubmed-meshheading:18549897-Half-Life, pubmed-meshheading:18549897-Humans, pubmed-meshheading:18549897-Liver Neoplasms, pubmed-meshheading:18549897-Osteopontin, pubmed-meshheading:18549897-Phenotype, pubmed-meshheading:18549897-Promoter Regions, Genetic, pubmed-meshheading:18549897-Protein Binding, pubmed-meshheading:18549897-RNA, Messenger, pubmed-meshheading:18549897-RNA Stability
pubmed:year	2008
pubmed:articleTitle	RNA stability regulates differential expression of the metastasis protein, osteopontin, in hepatocellular cancer.
pubmed:affiliation	Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural