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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2008-7-21
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pubmed:abstractText |
A series of fatty acid monoester derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) were prepared by one-pot lipase-catalyzed transesterification. The introduction of long alkyl chains enhanced anti-influenza A/PR8/34 (H1N1) virus activity 24-fold relative to native EGCG.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1464-3405
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:day |
15
|
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pubmed:volume |
18
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
4249-52
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18547804-Animals,
pubmed-meshheading:18547804-Antiviral Agents,
pubmed-meshheading:18547804-Catalysis,
pubmed-meshheading:18547804-Catechin,
pubmed-meshheading:18547804-Chemistry, Pharmaceutical,
pubmed-meshheading:18547804-Detergents,
pubmed-meshheading:18547804-Dogs,
pubmed-meshheading:18547804-Drug Design,
pubmed-meshheading:18547804-Fatty Acids,
pubmed-meshheading:18547804-Flavonoids,
pubmed-meshheading:18547804-Influenza A Virus, H1N1 Subtype,
pubmed-meshheading:18547804-Models, Chemical,
pubmed-meshheading:18547804-Phenols,
pubmed-meshheading:18547804-Polyphenols,
pubmed-meshheading:18547804-Solubility,
pubmed-meshheading:18547804-Water
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|
pubmed:year |
2008
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pubmed:articleTitle |
Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: effect of alkyl chain length.
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|
pubmed:affiliation |
The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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