Linked Life Data

18544503

Source:http://linkedlifedata.com/resource/pubmed/id/18544503

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-6-11
pubmed:abstractText
Endocytosis, an essential process of all eukaryotic cells, requires the actin cytoskeleton for proper functioning. The soil amoeba Dictyostelium discoideum is well known for its contribution to the actin cytoskeleton field. The genetic tractability and the availability of appropriate tools have made of Dictyostelium an attractive model for studies of endocytosis and vesicle trafficking as well. These tools include a large palette of fluorescent protein fusions and the combination of improved fractionation methods with high throughput techniques along with the recently propagated use of the amoeba a host for microbial pathogens. In this review I discuss in a comprehensive manner the evidence accumulated in the literature towards a participation of components of the microfilament system of D. discoideum in endocytic trafficking and conclude with a model that describes the sequence of events and the components involved during the well-investigated uptake phase of the endocytic process in the soil amoeba.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1937-6448
pubmed:author
pubmed:issnType
Print
pubmed:volume
267
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-97
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Endocytosis and the actin cytoskeleton in Dictyostelium discoideum.
pubmed:affiliation
The Hull York Medical School and Department of Biological Sciences, University of Hull, Hull HU6 7RX, United Kingdom.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't