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pubmed:abstractText |
The astonishing density of microbes in the mammalian gut has raised numerous questions, including how such colonization is tolerated in an immunocompetent location. Clearly the organisms perform a beneficial role, but until now the mechanisms have been less than clear. In a recent study in Nature, Mazmanian et al. (2008) reveal the ability of specific moieties on the surface of Bacteroides fragilis to direct the host's immune response.
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