Linked Life Data

18541117

Source:http://linkedlifedata.com/resource/pubmed/id/18541117

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-6-10
pubmed:abstractText
Leukodystrophies are a group of orphan genetic diseases that primarily affect the white matter (WM) of the brain. The diagnosis and classification of these pathologies have been improved in the past decade thanks to the development of brain MRI, which allows the diagnosis of WM abnormalities in vivo and the continuous follow-up of patients. This article reviews recent advances made in leukodystrophy research by identifying causative genes. It focuses particularly on the genes involved in the hypomyelinated and vacuolating leukodystrophies, which provide new insights into the understanding of myelin formation and WM homeostasis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1534-6293
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-29
pubmed:dateRevised
2008-8-25
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Genes involved in leukodystrophies: a glance at glial functions.
pubmed:affiliation
GReD, INSERM U931 CNRS 6247, Faculté de Médecine, 28, place Henri Dunant, 63000 Clermont-Ferrand, France. odile.boespflug@u-clermont1.fr
pubmed:publicationType
Journal Article, Review