Linked Life Data

18539245

Source:http://linkedlifedata.com/resource/pubmed/id/18539245

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-6-9
pubmed:abstractText
Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology with heterogeneous outcome. Based on the natural history or clinical treatment course, the outcomes of cases can be divided into two wings: spontaneous regression (self-limited disease) or progression of extensive fibrotic lesions as a postgranulomatous fibrosis. In addition to examining these outcomes, this article focuses on several related concepts, including chronicity (persistence of the lesions), relapse/recurrence, deterioration, and mortality. It also reviews the outcomes from the point of view of relevant clinical phenotypes, the natural disease course, the effects of treatment, and the effects of lung transplantation. Finally, it considers the effects of pulmonary hypertension, various genetic factors on the outcomes, and the efficacy of several novel therapeutic drugs in treating sarcoidosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0272-5231
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
565-74, x
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Outcome of sarcoidosis.
pubmed:affiliation
Central Clinic/Research Center, Masuyacho 56-58, Sanjou-Takakura, Nakagyoku, Kyoto, Japan. nagai@chuo-c.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't