rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-8-19
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pubmed:abstractText |
Alimentary tract (AT) mucositis is a serious complication of cancer treatment. Determining changes that occur in the AT can be difficult as invasive procedures are usually contraindicated in these patients. Changes in tissue levels of the transcription factor NFkappaB and pro-inflammatory cytokines have been demonstrated. The aims of this study were to determine whether changes in serum levels of NFkappaB, TNF, IL-1beta and IL-6 following administration of different drugs predicted histological evidence of tissue damage.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
1555-8576
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
7
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1139-45
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pubmed:meshHeading |
pubmed-meshheading:18535404-Animals,
pubmed-meshheading:18535404-Antineoplastic Agents,
pubmed-meshheading:18535404-Camptothecin,
pubmed-meshheading:18535404-Cytokines,
pubmed-meshheading:18535404-Epithelium,
pubmed-meshheading:18535404-Female,
pubmed-meshheading:18535404-Fluorouracil,
pubmed-meshheading:18535404-Gastrointestinal Tract,
pubmed-meshheading:18535404-Gene Expression Regulation,
pubmed-meshheading:18535404-Inflammation,
pubmed-meshheading:18535404-Interleukin-1beta,
pubmed-meshheading:18535404-Interleukin-6,
pubmed-meshheading:18535404-Methotrexate,
pubmed-meshheading:18535404-NF-kappa B,
pubmed-meshheading:18535404-Rats,
pubmed-meshheading:18535404-Tumor Necrosis Factor-alpha
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pubmed:year |
2008
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pubmed:articleTitle |
Serum levels of NFkappaB and pro-inflammatory cytokines following administration of mucotoxic drugs.
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pubmed:affiliation |
Oral Pathology, School of Dentistry, Faculty of Health Sciences, The University of Adelaide, South Australia, Australia. richard.logan@adelaide.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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