Linked Life Data

18528711

Source:http://linkedlifedata.com/resource/pubmed/id/18528711

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-9-26
pubmed:abstractText
A mother and her son, both with tubulointerstitial nephritis and uveitis syndrome (TINU) are reported. The nephritis presented itself at 13 years in the mother and at 10 years in her son. Glomerular filtration (GFR) decreased in both, and renal biopsies confirmed the diagnosis. Nephritis preceded the onset of uveitis in both. Clinical course and renal function improved quickly on oral steroids in the boy. The mother's hyperazotemia decreased spontaneously (without steroids), but not to normal range, and remained stable for 35 years of follow-up. Local steroids due to recurrences of uveitis were repeatedly needed in both. We believe this is the first report on familial occurrence of inherited TINU syndrome in two generations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0931-041X
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2091-3
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Tubulointerstitial nephritis and uveitis syndrome in a mother and her son.
pubmed:affiliation
Department of Pediatrics, University Hospital Motol, Charles University, 2nd Medical School, Prague, Czech Republic. j.dusek@lfmotol.cuni.cz
pubmed:publicationType
Journal Article, Case Reports