Linked Life Data

18522427

Source:http://linkedlifedata.com/resource/pubmed/id/18522427

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2008-6-27
pubmed:abstractText
The divergent synthesis of a 21-member library composed of 2-aminoimidazole compounds for evaluation as novel antibiofilm molecules is presented. The Sonogashira reaction was employed with three regioisomeric aryl iodides and 11 different alkynes to generate variously substituted diverse ring systems. Good to excellent yields (80-97%) for the reaction were obtained, and the products provide adequate handles for further manipulation into more advanced analogues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1520-6904
pubmed:author
pubmed:issnType
Electronic
pubmed:day
4
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5191-3
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Synthesis of a 2-aminoimidazole library for antibiofilm screening utilizing the Sonogashira reaction.
pubmed:affiliation
Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't