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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2008-11-21
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pubmed:abstractText |
Clinical, serological, and molecular data support the existence of discrete subsets of Crohn's disease (CD) defined by location of disease. Little is known about the epidemiology and natural history of isolated CD of the colon (Montreal Classification L2) because most studies have not accurately distinguished it from ileocolonic disease. Our objectives were to describe the clinical features and natural history of isolated colonic CD in a rigorously characterized patient cohort and to investigate the association of polymorphisms in a number of genes with colonic location of disease and disease behavior.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATG16L1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Genetic Markers,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DRB1 Chains,
http://linkedlifedata.com/resource/pubmed/chemical/IL23R protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MAP Kinase Kinase Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/MAP3K1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/NOD1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/NOD2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nod1 Signaling Adaptor Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Nod2 Signaling Adaptor Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1536-4844
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pubmed:author |
pubmed-author:AhmadTariqT,
pubmed-author:BecklyJohnJ,
pubmed-author:CooneyRachelR,
pubmed-author:CummingsFraserF,
pubmed-author:GeremiaAlessandraA,
pubmed-author:GuoChangunC,
pubmed-author:HancockLauraL,
pubmed-author:JewellDerekD,
pubmed-author:MortensenNeilN,
pubmed-author:PathanSaadS,
pubmed-author:WarrenBryan FBF
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pubmed:issnType |
Electronic
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1667-77
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18521924-Adolescent,
pubmed-meshheading:18521924-Adult,
pubmed-meshheading:18521924-Aged,
pubmed-meshheading:18521924-Carrier Proteins,
pubmed-meshheading:18521924-Case-Control Studies,
pubmed-meshheading:18521924-Child,
pubmed-meshheading:18521924-Child, Preschool,
pubmed-meshheading:18521924-Cohort Studies,
pubmed-meshheading:18521924-Colitis, Ulcerative,
pubmed-meshheading:18521924-Crohn Disease,
pubmed-meshheading:18521924-Female,
pubmed-meshheading:18521924-Genetic Markers,
pubmed-meshheading:18521924-Genotype,
pubmed-meshheading:18521924-HLA-DR Antigens,
pubmed-meshheading:18521924-HLA-DRB1 Chains,
pubmed-meshheading:18521924-Humans,
pubmed-meshheading:18521924-MAP Kinase Kinase Kinase 1,
pubmed-meshheading:18521924-Male,
pubmed-meshheading:18521924-Middle Aged,
pubmed-meshheading:18521924-Nod1 Signaling Adaptor Protein,
pubmed-meshheading:18521924-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:18521924-Polymerase Chain Reaction,
pubmed-meshheading:18521924-Polymorphism, Single Nucleotide,
pubmed-meshheading:18521924-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:18521924-Receptors, Interleukin,
pubmed-meshheading:18521924-Survival Rate,
pubmed-meshheading:18521924-Young Adult
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pubmed:year |
2008
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pubmed:articleTitle |
Clinical and molecular characteristics of isolated colonic Crohn's disease.
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pubmed:affiliation |
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. laurahancock@doctors.org.uk
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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