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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2008-10-27
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pubmed:abstractText |
Loss of heterozygosity (LOH) in a chromosomal location indicates the presence of an inactivated tumor suppressor gene (TSG). Inactivation of TSG has a functional role in the tumorigenesis of head and neck squamous cell carcinoma (HNSCC). Based on the recent evidences of a putative TSG on chromosome 14, we examined LOH on chromosome 14q using eight polymorphic microsatellite markers in 50 cases of HNSCCs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1432-1335
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pubmed:author |
pubmed-author:BederLevent BekirLB,
pubmed-author:CengizBeyhanB,
pubmed-author:FukushimaKunihiroK,
pubmed-author:GunduzEsraE,
pubmed-author:GunduzMehmetM,
pubmed-author:NagatsukaHitoshiH,
pubmed-author:OzturkSukruS,
pubmed-author:PalanduzSukruS,
pubmed-author:PehlivanDavutD,
pubmed-author:RiveraRosario SRS,
pubmed-author:ShimizuKenjiK,
pubmed-author:YamanakaNoboruN
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pubmed:issnType |
Electronic
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pubmed:volume |
134
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1267-76
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pubmed:dateRevised |
2009-3-17
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pubmed:meshHeading |
pubmed-meshheading:18521630-Aged,
pubmed-meshheading:18521630-Carcinoma, Squamous Cell,
pubmed-meshheading:18521630-Case-Control Studies,
pubmed-meshheading:18521630-Chromosome Deletion,
pubmed-meshheading:18521630-Chromosome Mapping,
pubmed-meshheading:18521630-Chromosomes, Human, Pair 14,
pubmed-meshheading:18521630-Female,
pubmed-meshheading:18521630-Genes, Tumor Suppressor,
pubmed-meshheading:18521630-Head and Neck Neoplasms,
pubmed-meshheading:18521630-Humans,
pubmed-meshheading:18521630-Loss of Heterozygosity,
pubmed-meshheading:18521630-Male,
pubmed-meshheading:18521630-Microsatellite Repeats,
pubmed-meshheading:18521630-Middle Aged,
pubmed-meshheading:18521630-Prognosis,
pubmed-meshheading:18521630-Survival Rate
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pubmed:year |
2008
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pubmed:articleTitle |
Loss of heterozygosity at chromosome 14q is associated with poor prognosis in head and neck squamous cell carcinomas.
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pubmed:affiliation |
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Shikatacho 2-5-1, Okayama 700-8525, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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