Source:http://linkedlifedata.com/resource/pubmed/id/18520164
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2008-6-3
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pubmed:abstractText |
Fluorescence molecular brain imaging is a new modality allowing the detection of specific contrast agents down to very low concentration ranges (picomolar) in disease models. Here we demonstrate a first noninvasive application of fluorescence imaging in the human brain, where concentrations down to about 100 nM of a nonspecific dye were detected. We argue that due to its high sensitivity, optical molecular imaging of the brain is feasible, which - together with its bedside applicability - makes it a promising technique for use in patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1660-2862
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pubmed:author |
pubmed-author:BeugHH,
pubmed-author:BourayouRR,
pubmed-author:DirnaglUU,
pubmed-author:KlohsJJ,
pubmed-author:LiebertAA,
pubmed-author:LindauerUU,
pubmed-author:MacdonaldRR,
pubmed-author:ObrigHH,
pubmed-author:SteinbrinkJJ,
pubmed-author:VillringerAA,
pubmed-author:WabnitzHH,
pubmed-author:WunderAA
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pubmed:copyrightInfo |
(c) 2008 S. Karger AG, Basel
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
296-303
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pubmed:meshHeading |
pubmed-meshheading:18520164-Animals,
pubmed-meshheading:18520164-Brain,
pubmed-meshheading:18520164-Fluorescence,
pubmed-meshheading:18520164-Humans,
pubmed-meshheading:18520164-Mice,
pubmed-meshheading:18520164-Molecular Biology,
pubmed-meshheading:18520164-Sensitivity and Specificity,
pubmed-meshheading:18520164-Spectroscopy, Near-Infrared
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pubmed:year |
2008
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pubmed:articleTitle |
Towards noninvasive molecular fluorescence imaging of the human brain.
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pubmed:affiliation |
Clinic of Neurology, Charité - Universitatsmedizin Berlin, Berlin, Germany. jens.steinbrink@charite.de
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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