18519795

Source:http://linkedlifedata.com/resource/pubmed/id/18519795

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011209, umls-concept:C0013216, umls-concept:C0027651, umls-concept:C0079925, umls-concept:C0215848, umls-concept:C0599894, umls-concept:C1521840, umls-concept:C2003941, umls-concept:C2349975
pubmed:issue	11
pubmed:dateCreated	2008-6-3
pubmed:abstractText	To enhance the efficacy of cancer treatment, we propose a complex approach: simultaneous delivery to the tumor of a chemotherapeutic agent and a suppressor of hypoxia-inducible factor 1 alpha (HIF1A).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/CA074175, http://linkedlifedata.com/resource/pubmed/grant/CA100098, http://linkedlifedata.com/resource/pubmed/grant/CA111766
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin, http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1, alpha..., http://linkedlifedata.com/resource/pubmed/chemical/Oligonucleotides, Antisense
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1078-0432
pubmed:author	pubmed-author:GarbuzenkoOlga BOB, pubmed-author:KhandareJayant JJJ, pubmed-author:MinkoTamaraT, pubmed-author:PakunluRefika IRI, pubmed-author:PozharovVitaly PVP, pubmed-author:SaadMahaM, pubmed-author:SoldatenkovViatcheslav AVA, pubmed-author:VetcherAlexandre AAA, pubmed-author:WangYangY
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	14
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	3607-16
pubmed:meshHeading	pubmed-meshheading:18519795-Animals, pubmed-meshheading:18519795-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:18519795-Blotting, Western, pubmed-meshheading:18519795-Cell Line, Tumor, pubmed-meshheading:18519795-Doxorubicin, pubmed-meshheading:18519795-Drug Delivery Systems, pubmed-meshheading:18519795-Drug Resistance, Neoplasm, pubmed-meshheading:18519795-Female, pubmed-meshheading:18519795-Humans, pubmed-meshheading:18519795-Hypoxia-Inducible Factor 1, alpha Subunit, pubmed-meshheading:18519795-Mice, pubmed-meshheading:18519795-Microscopy, Atomic Force, pubmed-meshheading:18519795-Microscopy, Electron, Transmission, pubmed-meshheading:18519795-Nanoparticles, pubmed-meshheading:18519795-Oligonucleotides, Antisense, pubmed-meshheading:18519795-Ovarian Neoplasms, pubmed-meshheading:18519795-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:18519795-Xenograft Model Antitumor Assays
pubmed:year	2008
pubmed:articleTitle	Nonviral nanoscale-based delivery of antisense oligonucleotides targeted to hypoxia-inducible factor 1 alpha enhances the efficacy of chemotherapy in drug-resistant tumor.
pubmed:affiliation	Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854-8020, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural