18518979

Source:http://linkedlifedata.com/resource/pubmed/id/18518979

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006142, umls-concept:C0034804, umls-concept:C0086418, umls-concept:C1314939, umls-concept:C1336927, umls-concept:C1514559, umls-concept:C1515877, umls-concept:C1879547
pubmed:dateCreated	2008-6-19
pubmed:abstractText	Our previous study revealed that Vav3 oncogene is overexpressed in human prostate cancer, activates androgen receptor, and stimulates growth in prostate cancer cells. The current study is to determine a potential role of Vav3 oncogene in human breast cancer and impact on estrogen receptor a (ERalpha)-mediated signaling axis.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R01 CA119935-02, http://linkedlifedata.com/resource/pubmed/grant/R01CA119935
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100967800
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Epidermal Growth Factor, http://linkedlifedata.com/resource/pubmed/chemical/Estrogen Receptor alpha, http://linkedlifedata.com/resource/pubmed/chemical/Guanine Nucleotide Exchange Factors, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-vav, http://linkedlifedata.com/resource/pubmed/chemical/VAV3 protein, human
pubmed:status	MEDLINE
pubmed:issn	1471-2407
pubmed:author	pubmed-author:DongZhongyunZ, pubmed-author:LeeKiwonK, pubmed-author:LiuYinY, pubmed-author:MoJun QinJQ, pubmed-author:SeulBB, pubmed-author:ZhangJinsongJ
pubmed:issnType	Electronic
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	158
pubmed:dateRevised	2011-9-26
pubmed:meshHeading	pubmed-meshheading:18518979-Breast Neoplasms, pubmed-meshheading:18518979-Cell Growth Processes, pubmed-meshheading:18518979-Cell Line, Tumor, pubmed-meshheading:18518979-Epidermal Growth Factor, pubmed-meshheading:18518979-Estrogen Receptor alpha, pubmed-meshheading:18518979-Gene Expression Regulation, Neoplastic, pubmed-meshheading:18518979-Guanine Nucleotide Exchange Factors, pubmed-meshheading:18518979-HeLa Cells, pubmed-meshheading:18518979-Humans, pubmed-meshheading:18518979-Immunohistochemistry, pubmed-meshheading:18518979-Phosphatidylinositol 3-Kinases, pubmed-meshheading:18518979-Proto-Oncogene Proteins c-akt, pubmed-meshheading:18518979-Proto-Oncogene Proteins c-vav, pubmed-meshheading:18518979-Signal Transduction, pubmed-meshheading:18518979-Up-Regulation
pubmed:year	2008
pubmed:articleTitle	Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer.
pubmed:affiliation	Department of Pathology, University of Cincinnati College of Medicine, 2120 E, Galbraith Road, Cincinnati, OH 45237, USA. leeko@UCMAIL.UC.EDU
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural