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rdf:type |
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lifeskim:mentions |
umls-concept:C0007595,
umls-concept:C0010453,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0057252,
umls-concept:C0162638,
umls-concept:C0205263,
umls-concept:C0227651,
umls-concept:C0237477,
umls-concept:C1514559,
umls-concept:C1533691
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pubmed:issue |
7
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pubmed:dateCreated |
2009-1-23
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pubmed:abstractText |
Decorin (DCN) is a small leucine-rich proteoglycan that plays an important role in the regulation of intercellular contact, cell migration and proliferation. DCN suppresses cell growth and induces apoptosis in various tumour cells. The aim of this study was to investigate whether overexpression of DCN could induce apoptosis and cell growth arrest in mesangial cells (MsCs) in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Cdkn1a protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Dcn protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Decorin,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proteoglycans,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta1
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1440-1797
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
607-15
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18518935-Animals,
pubmed-meshheading:18518935-Apoptosis,
pubmed-meshheading:18518935-Caspase 3,
pubmed-meshheading:18518935-Cell Cycle,
pubmed-meshheading:18518935-Cell Proliferation,
pubmed-meshheading:18518935-Cells, Cultured,
pubmed-meshheading:18518935-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:18518935-Decorin,
pubmed-meshheading:18518935-Extracellular Matrix Proteins,
pubmed-meshheading:18518935-Flow Cytometry,
pubmed-meshheading:18518935-Male,
pubmed-meshheading:18518935-Mesangial Cells,
pubmed-meshheading:18518935-Proteoglycans,
pubmed-meshheading:18518935-RNA, Small Interfering,
pubmed-meshheading:18518935-Rats,
pubmed-meshheading:18518935-Rats, Sprague-Dawley,
pubmed-meshheading:18518935-Receptor, Epidermal Growth Factor,
pubmed-meshheading:18518935-Transforming Growth Factor beta1
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pubmed:year |
2008
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pubmed:articleTitle |
Overexpression of decorin induces apoptosis and cell growth arrest in cultured rat mesangial cells in vitro.
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pubmed:affiliation |
Department of Pathology and Key Laboratory of Molecular Medicine, Ministry of Education of China, Fudan University, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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