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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2008-8-22
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pubmed:abstractText |
MUTYH-associated polyposis (MAP) is a recessive trait characterised by multiple colorectal adenomas and a high risk of colorectal cancer. MUTYH functions in the DNA base excision repair pathway and has a key role in the repair of oxidative DNA damage.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/8-oxodGTPase,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Glycosylases,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Repair Enzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxyribonuclease (Pyrimidine Dimer),
http://linkedlifedata.com/resource/pubmed/chemical/NTHL1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoric Monoester Hydrolases,
http://linkedlifedata.com/resource/pubmed/chemical/mutY adenine glycosylase,
http://linkedlifedata.com/resource/pubmed/chemical/oxoguanine glycosylase 1, human
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1468-3288
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pubmed:author |
pubmed-author:ArnoldJJ,
pubmed-author:CheadleJ PJP,
pubmed-author:ColleyJJ,
pubmed-author:DallossoA RAR,
pubmed-author:DolwaniSS,
pubmed-author:DonaldsonAA,
pubmed-author:EcclesDD,
pubmed-author:EllisAA,
pubmed-author:EvansD GDG,
pubmed-author:FraylingI MIM,
pubmed-author:HoulstonR SRS,
pubmed-author:HumphreysVV,
pubmed-author:IdziaszczykSS,
pubmed-author:JonesNN,
pubmed-author:JonesSS,
pubmed-author:MaherE RER,
pubmed-author:MaynardJJ,
pubmed-author:MoskvinaVV,
pubmed-author:NielsenMM,
pubmed-author:ParrySS,
pubmed-author:SampsonJ RJR,
pubmed-author:TylerEE,
pubmed-author:YeeW HWH
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pubmed:issnType |
Electronic
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1252-5
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pubmed:meshHeading |
pubmed-meshheading:18515411-Adenomatous Polyposis Coli,
pubmed-meshheading:18515411-Adolescent,
pubmed-meshheading:18515411-Adult,
pubmed-meshheading:18515411-Aged,
pubmed-meshheading:18515411-Alleles,
pubmed-meshheading:18515411-DNA Glycosylases,
pubmed-meshheading:18515411-DNA Repair Enzymes,
pubmed-meshheading:18515411-Deoxyribonuclease (Pyrimidine Dimer),
pubmed-meshheading:18515411-Genes, Recessive,
pubmed-meshheading:18515411-Genetic Predisposition to Disease,
pubmed-meshheading:18515411-Humans,
pubmed-meshheading:18515411-Middle Aged,
pubmed-meshheading:18515411-Mutation,
pubmed-meshheading:18515411-Neoplasm Proteins,
pubmed-meshheading:18515411-Phenotype,
pubmed-meshheading:18515411-Phosphoric Monoester Hydrolases,
pubmed-meshheading:18515411-Polymerase Chain Reaction,
pubmed-meshheading:18515411-Registries
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pubmed:year |
2008
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pubmed:articleTitle |
Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3.
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pubmed:affiliation |
Institute of Medical Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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