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pubmed-article:18515308pubmed:abstractTextBoth the phenotypic alterations of parathyroid (PT) cells, e.g. down-regulation of the calcium-sensing receptor, and the increase of the PT cell number in nodular hyperplasia are the main causes of refractory secondary hyperparathyroidism. It is of great importance to prevent PT growth in an early stage.lld:pubmed
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pubmed-article:18515308pubmed:articleTitleIntravenous calcitriol therapy in an early stage prevents parathyroid gland growth.lld:pubmed
pubmed-article:18515308pubmed:affiliationDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Higashi-Ku, Fukuoka 812-8582, Japan. masatomo@kcu.med.kyushu-u.ac.jplld:pubmed
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