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rdf:type |
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lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0015576,
umls-concept:C0035647,
umls-concept:C0205210,
umls-concept:C0376571,
umls-concept:C0524899,
umls-concept:C0542559,
umls-concept:C0598034,
umls-concept:C0677578,
umls-concept:C0679560,
umls-concept:C0694768,
umls-concept:C0750572,
umls-concept:C1140680,
umls-concept:C1516167,
umls-concept:C1527178,
umls-concept:C1705938
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pubmed:dateCreated |
2008-7-10
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pubmed:abstractText |
The identification of a BRCA1 or BRCA2 mutation in familial breast cancer kindreds allows genetic testing of at risk relatives. However, considerable controversy exists regarding the cancer risks in women who test positive for the family mutation.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-10413426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-10433620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-10498392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-11463009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-11927492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-12023993,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-12189225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-14576434,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-15131399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-15173236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-15994883,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-16284991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-16417652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-16418514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-16484695,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-17079251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-17466083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-17529967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-17529973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-17625127,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-7545954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-7907678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-8524414,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-9145676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18513387-9497246
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
155
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18513387-Adult,
pubmed-meshheading:18513387-Aged,
pubmed-meshheading:18513387-Aged, 80 and over,
pubmed-meshheading:18513387-Breast Neoplasms,
pubmed-meshheading:18513387-Family Health,
pubmed-meshheading:18513387-Female,
pubmed-meshheading:18513387-Genes, BRCA1,
pubmed-meshheading:18513387-Genes, BRCA2,
pubmed-meshheading:18513387-Genetic Predisposition to Disease,
pubmed-meshheading:18513387-Genetic Testing,
pubmed-meshheading:18513387-Germ-Line Mutation,
pubmed-meshheading:18513387-Humans,
pubmed-meshheading:18513387-Middle Aged,
pubmed-meshheading:18513387-Ovarian Neoplasms,
pubmed-meshheading:18513387-Penetrance,
pubmed-meshheading:18513387-Prospective Studies
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pubmed:year |
2008
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pubmed:articleTitle |
Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a Clinical Cancer Genetics service setting: risks of breast/ovarian cancer quoted should reflect the cancer burden in the family.
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pubmed:affiliation |
Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital Manchester M13 0JH, UK. gareth.evans@cmmc.nhs.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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