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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1991-6-7
|
| pubmed:abstractText |
Anti-HCV prevalence in treated hemophiliacs, their heterosexual partners, intravenous drug addicts and homosexual men was studied. In hemophiliacs and many of the intravenous drug addicts, greater than or equal to 2 sera drawn 1-18 or 1-17 years apart were available. Anti-HCV testing was performed by ELISA (Ortho). Among patients with severe and moderate hemophilia A, 87% (98/112) were positive for anti-HCV at least once and among patients with severe and moderate hemophilia B, 83% (24/29) were positive for anti-HCV. Seroconversion to anti-HCV was observed in 21% of hemophilia patients. In hemophilia A, HCV infection generally occurred during the first years of life and in hemophilia B somewhat later. Loss of anti-HCV antibody was seen in 12% (17 patients). The rest, 54% (76 patients) were seropositive in first and last samples. All 12 tested spouses to anti-HCV positive men were anti-HCV negative. 80% of the drug addicts (137/172) were seropositive for anti-HCV. In those with greater than 1 serum tested, 8% were consistently negative and 68% consistently positive. 21% seroconverted to anti-HCV while 3% lost antibody. 10% (22/211) of homosexual men were anti-HCV positive. Intravenous transmission of HCV thus seemed highly efficient whereas sexual transmission was much less efficient.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0036-5548
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
19-24
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1851322-Adolescent,
pubmed-meshheading:1851322-Adult,
pubmed-meshheading:1851322-Age Factors,
pubmed-meshheading:1851322-Child,
pubmed-meshheading:1851322-Child, Preschool,
pubmed-meshheading:1851322-Female,
pubmed-meshheading:1851322-Hemophilia A,
pubmed-meshheading:1851322-Hemophilia B,
pubmed-meshheading:1851322-Hepacivirus,
pubmed-meshheading:1851322-Hepatitis Antibodies,
pubmed-meshheading:1851322-Hepatitis B,
pubmed-meshheading:1851322-Hepatitis C,
pubmed-meshheading:1851322-Homosexuality,
pubmed-meshheading:1851322-Humans,
pubmed-meshheading:1851322-Infant,
pubmed-meshheading:1851322-Male,
pubmed-meshheading:1851322-Middle Aged,
pubmed-meshheading:1851322-Risk Factors,
pubmed-meshheading:1851322-Sexual Partners,
pubmed-meshheading:1851322-Substance Abuse, Intravenous
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Antibody to a hepatitis C virus related protein among patients at high risk for hepatitis B.
|
| pubmed:affiliation |
Department of Clinical Virology, Malmö General Hospital, Sweden.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|