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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2008-7-24
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pubmed:abstractText |
Gender and ethnicity modulate the phenotypic expression of cardiovascular risk factors. In particular, men are at higher risk of developing cardiovascular diseases compared to women, whereas black populations of African origin display reduced mortality from coronary heart disease (CHD) as compared to both whites and South Asians. Because the male-specific region (MSY) of the human Y chromosome is an obvious candidate for gender-related differences in the development of cardiovascular diseases, we aimed to identify genetic variants of MSY influencing cardiovascular risk profile in different ethnic groups.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1569-74
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pubmed:meshHeading |
pubmed-meshheading:18511697-African Continental Ancestry Group,
pubmed-meshheading:18511697-Asian Continental Ancestry Group,
pubmed-meshheading:18511697-Cholesterol, HDL,
pubmed-meshheading:18511697-Chromosomes, Human, Y,
pubmed-meshheading:18511697-Coronary Disease,
pubmed-meshheading:18511697-Cross-Sectional Studies,
pubmed-meshheading:18511697-European Continental Ancestry Group,
pubmed-meshheading:18511697-Haplotypes,
pubmed-meshheading:18511697-Humans,
pubmed-meshheading:18511697-Male,
pubmed-meshheading:18511697-Polymorphism, Single Nucleotide,
pubmed-meshheading:18511697-Transducin,
pubmed-meshheading:18511697-Triglycerides,
pubmed-meshheading:18511697-Ubiquitin Thiolesterase
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pubmed:year |
2008
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pubmed:articleTitle |
Genetic variants of Y chromosome are associated with a protective lipid profile in black men.
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pubmed:affiliation |
Unit of Epidemiology & Population Genetics, Institute of Food Sciences, CNR, Via Roma 52A/C, 83100, Avellino, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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