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| pubmed-article:1850972 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:1850972 | lifeskim:mentions | umls-concept:C0949782 | lld:lifeskim |
| pubmed-article:1850972 | lifeskim:mentions | umls-concept:C0032520 | lld:lifeskim |
| pubmed-article:1850972 | lifeskim:mentions | umls-concept:C0370215 | lld:lifeskim |
| pubmed-article:1850972 | lifeskim:mentions | umls-concept:C0205396 | lld:lifeskim |
| pubmed-article:1850972 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:1850972 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:1850972 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1850972 | pubmed:dateCreated | 1991-5-31 | lld:pubmed |
| pubmed-article:1850972 | pubmed:abstractText | Seven nalidixic acid-resistant clinical isolates of Escherichia coli were shown to carry resistance mutations in their gyrase A proteins. Six had serine-83 to leucine or tryptophan changes; the seventh had an aspartate-87 to valine substitution. The frequent occurrence of a mutation at serine-83 implies a key role for this residue in quinolone action. | lld:pubmed |
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| pubmed-article:1850972 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:1850972 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1850972 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1850972 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:1850972 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:1850972 | pubmed:author | pubmed-author:FisherL MLM | lld:pubmed |
| pubmed-article:1850972 | pubmed:author | pubmed-author:OramMM | lld:pubmed |
| pubmed-article:1850972 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1850972 | pubmed:volume | 35 | lld:pubmed |
| pubmed-article:1850972 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1850972 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1850972 | pubmed:pagination | 387-9 | lld:pubmed |
| pubmed-article:1850972 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1850972 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1850972 | pubmed:articleTitle | 4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction. | lld:pubmed |
| pubmed-article:1850972 | pubmed:affiliation | Department of Cellular and Molecular Sciences, St. George's Hospital Medical School, London, United Kingdom. | lld:pubmed |
| pubmed-article:1850972 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1850972 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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