Recent progress in the treatment of sickle cell disease, in particular the use of hydroxyurea, has considerably modified the prognosis of this disease. Many more patients now reach reproductive age. The objective of this study was to assess the potential impact of hydroxyurea on the semen of patients.
Service d'Histologie, Biologie de, la Reproduction et Cytogénétique, CECOS Hôpital Tenon 4, rue de la, Chine 75020 Paris, France. jacqueline.mandelbaum@tnn.aphp.fr.