Linked Life Data

18508388

Source:http://linkedlifedata.com/resource/pubmed/id/18508388

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2008-7-16
pubmed:abstractText
The mitochondrial flavoprotein apoptosis-inducing factor (AIF) has proved to be either the main mediator of apoptosis or an anti-apoptotic factor via its putative oxidoreductase and peroxide scavenging activities. We report here that 100 muM hydrogen peroxide (H2O2) induced the proliferation of C2C12 myoblasts and over-expression of AIF simultaneously in vitro. Immunofluorescence showed that the over-expression of AIF was located in the cytoplasm. The immunopositive AIF was detected in nuclei 27 days after denervation of skeletal muscle, but in the cytoplasm it was detected 27 days after fiber-damaged skeletal muscle. AIF may be a factor involved in skeletal muscle regeneration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1099-0844
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
598-602
pubmed:meshHeading
pubmed:articleTitle
Mitochondrial AIF protein involved in skeletal muscle regeneration.
pubmed:affiliation
Department of Anatomy, Southern Medical University, Guangdong Provinical Tissue Construction and Inspection Key Lab, Guangzhou, Guangdong, China. qqiuxzh@yahoo.com.cn
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't