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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-4-15
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pubmed:abstractText |
Several findings link systemic lupus erythematosus (SLE) with C1q, the first molecule of the classical complement pathway. Polymorphisms of the C1qA gene are associated with low serum C1q levels in patients with cutaneous LE, but C1q polymorphisms have not been studied in patients with systemic lupus.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1468-2060
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
715-20
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pubmed:meshHeading |
pubmed-meshheading:18504288-Adult,
pubmed-meshheading:18504288-Aged,
pubmed-meshheading:18504288-Chromosomes, Human, Pair 1,
pubmed-meshheading:18504288-Complement C1q,
pubmed-meshheading:18504288-Complement Hemolytic Activity Assay,
pubmed-meshheading:18504288-Complement Pathway, Classical,
pubmed-meshheading:18504288-Female,
pubmed-meshheading:18504288-Genetic Predisposition to Disease,
pubmed-meshheading:18504288-Haplotypes,
pubmed-meshheading:18504288-Humans,
pubmed-meshheading:18504288-Linkage Disequilibrium,
pubmed-meshheading:18504288-Lupus Erythematosus, Systemic,
pubmed-meshheading:18504288-Male,
pubmed-meshheading:18504288-Middle Aged,
pubmed-meshheading:18504288-Polymorphism, Single Nucleotide,
pubmed-meshheading:18504288-Severity of Illness Index,
pubmed-meshheading:18504288-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Analysis of C1q polymorphisms suggests association with systemic lupus erythematosus, serum C1q and CH50 levels and disease severity.
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pubmed:affiliation |
Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. h.a.martens@int.umcg.nl
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pubmed:publicationType |
Journal Article
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