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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-7-2
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pubmed:abstractText |
Seborrhoeic keratosis (SK) represents one of the most common benign skin tumours. Familial occurrence of multiple SKs has been reported, but the genetic basis of these SKs has not been investigated so far. We present a German family with at least seven affected members in two generations and occurrence of high numbers of SKs at an unusually young age, suggesting a hereditary background.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1365-2133
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
159
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
214-7
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18503601-Adult,
pubmed-meshheading:18503601-DNA Mutational Analysis,
pubmed-meshheading:18503601-Exons,
pubmed-meshheading:18503601-Family,
pubmed-meshheading:18503601-Female,
pubmed-meshheading:18503601-Genetic Predisposition to Disease,
pubmed-meshheading:18503601-Germ-Line Mutation,
pubmed-meshheading:18503601-Humans,
pubmed-meshheading:18503601-Keratosis, Seborrheic,
pubmed-meshheading:18503601-Male,
pubmed-meshheading:18503601-Middle Aged,
pubmed-meshheading:18503601-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:18503601-Receptor, Fibroblast Growth Factor, Type 3,
pubmed-meshheading:18503601-Risk Factors,
pubmed-meshheading:18503601-Skin Neoplasms
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pubmed:year |
2008
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pubmed:articleTitle |
Somatic FGFR3 and PIK3CA mutations are present in familial seborrhoeic keratoses.
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pubmed:affiliation |
Department of Dermatology, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany. christian.hafner@klinik.uni-regensburg.de
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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