Source:http://linkedlifedata.com/resource/pubmed/id/18502088
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-1-21
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pubmed:abstractText |
Most patients with locally advanced primary breast cancer have micrometastases at the time of presentation. Randomised trials on the use of neoadjuvant chemotherapy have not been carried out specifically in a population of breast cancer patients with locally advanced disease (LAPC). Despite this, its use for cytoreduction in these patients is an established option which may facilitate excision of the primary tumour and local lymph node metastasis for local control. Significant improvements in local disease control have been seen with recent advances in systemic chemotherapy regimens although thus far this has not shown in randomised trials to translate into overall survival benefits.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1532-2157
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-22
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pubmed:meshHeading |
pubmed-meshheading:18502088-Antineoplastic Agents,
pubmed-meshheading:18502088-Breast Neoplasms,
pubmed-meshheading:18502088-Chemotherapy, Adjuvant,
pubmed-meshheading:18502088-Female,
pubmed-meshheading:18502088-Humans,
pubmed-meshheading:18502088-Mastectomy,
pubmed-meshheading:18502088-Neoadjuvant Therapy,
pubmed-meshheading:18502088-Survival Rate,
pubmed-meshheading:18502088-Treatment Outcome,
pubmed-meshheading:18502088-World Health
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pubmed:year |
2009
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pubmed:articleTitle |
Neoadjuvant chemotherapy for locally advanced breast cancer: a review of the literature and future directions.
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pubmed:affiliation |
Professorial Unit of Surgery, Nottingham University Hospital, Nottingham, UK. mathewjohn9@aol.com
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pubmed:publicationType |
Journal Article,
Review
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