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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-6-12
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pubmed:abstractText |
Aberrant DNA hypermethylation has been reported in renal cell carcinoma. We performed microarray analysis in the renal cancer cell line ACHN treated with the demethylating agent 5-aza-2'-deoxycytidine and investigated the UCHL1 gene involved in the regulation of cellular ubiquitin levels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1527-3792
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pubmed:author |
pubmed-author:ChiyomaruTakeshiT,
pubmed-author:EnokidaHidekiH,
pubmed-author:ItesakoToshihikoT,
pubmed-author:KagaraIchiroI,
pubmed-author:KawakamiKazumoriK,
pubmed-author:KawamotoKenK,
pubmed-author:MatsudaRyouichirouR,
pubmed-author:NakagawaMasayukiM,
pubmed-author:NishimuraHiroakiH,
pubmed-author:NishiyamaKenryuK,
pubmed-author:SekiNaohikoN,
pubmed-author:TataranoShuichiS,
pubmed-author:TokiKazukiK
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pubmed:issnType |
Electronic
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pubmed:volume |
180
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-51
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18499164-Carcinoma, Renal Cell,
pubmed-meshheading:18499164-Cell Line, Tumor,
pubmed-meshheading:18499164-CpG Islands,
pubmed-meshheading:18499164-DNA Methylation,
pubmed-meshheading:18499164-Humans,
pubmed-meshheading:18499164-Kidney Neoplasms,
pubmed-meshheading:18499164-Prognosis,
pubmed-meshheading:18499164-Promoter Regions, Genetic,
pubmed-meshheading:18499164-Ubiquitin Thiolesterase
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pubmed:year |
2008
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pubmed:articleTitle |
CpG hypermethylation of the UCHL1 gene promoter is associated with pathogenesis and poor prognosis in renal cell carcinoma.
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pubmed:affiliation |
Department of Urology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
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pubmed:publicationType |
Journal Article
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