Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1977-1-3
|
pubmed:abstractText |
A comparison of the ability of vesicular stomatitis virus (VSV) to generate and replicate defective interfering (DI) particles in primary chick embryo (CE) and mouse L cells was investigated as a means of analyzing host control over DI-particle synthesis and interfering capacity. Serial undiluted passage of VSV in CE and L cells indicate that VSV-DI particles are generated and (or) replicate with greater efficiency in CE than in L cells. When DI particles accumulate in L cells, they are able to interfere with infectious particle replication. The DI particles from CE cells interfered to the same extent with infectious particle replication in both CE and L cells. L cells, therefore, are not considered 'low-interference' hosts in which DI particles are produced and do not interfere with infectious virus replication, but rather hosts which restrict the production of DI particles.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0008-4166
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1458-63
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:184896-Animals,
pubmed-meshheading:184896-Chick Embryo,
pubmed-meshheading:184896-Culture Techniques,
pubmed-meshheading:184896-Defective Viruses,
pubmed-meshheading:184896-L Cells (Cell Line),
pubmed-meshheading:184896-Vesicular stomatitis Indiana virus,
pubmed-meshheading:184896-Viral Interference,
pubmed-meshheading:184896-Virus Replication
|
pubmed:year |
1976
|
pubmed:articleTitle |
Comparison of vesicular stomatitis virus defective interfering particle synthesis in chick embryo and L cells.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|