rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2008-5-23
|
pubmed:abstractText |
Cyclooxygenase (COX)-2 is an inducible enzyme responsible for catalysing the formation of prostaglandins (PGs) in settings of inflammation. Single nucleotide polymorphisms (SNPs) of the COX-2 gene may influence gene transcription and PG production in the asthmatic airway.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1365-2222
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
913-20
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:18489027-Adult,
pubmed-meshheading:18489027-Aged,
pubmed-meshheading:18489027-Aged, 80 and over,
pubmed-meshheading:18489027-Aspirin,
pubmed-meshheading:18489027-Asthma,
pubmed-meshheading:18489027-Australia,
pubmed-meshheading:18489027-Case-Control Studies,
pubmed-meshheading:18489027-Cyclooxygenase 2,
pubmed-meshheading:18489027-European Continental Ancestry Group,
pubmed-meshheading:18489027-Female,
pubmed-meshheading:18489027-Gene Frequency,
pubmed-meshheading:18489027-Genetic Predisposition to Disease,
pubmed-meshheading:18489027-Haplotypes,
pubmed-meshheading:18489027-HeLa Cells,
pubmed-meshheading:18489027-Humans,
pubmed-meshheading:18489027-Male,
pubmed-meshheading:18489027-Middle Aged,
pubmed-meshheading:18489027-Phenotype,
pubmed-meshheading:18489027-Plasmids,
pubmed-meshheading:18489027-Polymerase Chain Reaction,
pubmed-meshheading:18489027-Polymorphism, Single Nucleotide,
pubmed-meshheading:18489027-Promoter Regions, Genetic,
pubmed-meshheading:18489027-Sequence Analysis, DNA,
pubmed-meshheading:18489027-Transfection
|
pubmed:year |
2008
|
pubmed:articleTitle |
Cyclooxygenase-2 gene polymorphisms in an Australian population: association of the -1195G > A promoter polymorphism with mild asthma.
|
pubmed:affiliation |
Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, WA, Australia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|