| pubmed-article:1848698 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C0042769 | lld:lifeskim |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C0036638 | lld:lifeskim |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C0039195 | lld:lifeskim |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C1996904 | lld:lifeskim |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C1880497 | lld:lifeskim |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:1848698 | lifeskim:mentions | umls-concept:C0597551 | lld:lifeskim |
| pubmed-article:1848698 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:1848698 | pubmed:dateCreated | 1991-4-25 | lld:pubmed |
| pubmed-article:1848698 | pubmed:abstractText | The only peptide of Sendai virus that is recognized by cytotoxic T lymphocytes (CTL) in B6 mice was found with (i) the use of recombinant vaccinia virus constructs containing separate genes of Sendai virus and (ii) a set of overlapping peptides completely spanning the identified nucleoprotein (NP) gene product. This immunodominant NP peptide is recognized by Sendai virus-specific CTL that are known to have therapeutic effects in vivo. By subcutaneous immunization, this peptide induced Sendai virus and NP peptide-specific CTL memory responses in vivo. Most importantly, mice that had been immunized with this peptide were protected against a lethal virus dose, indicating that viral peptides can be used as antiviral T-cell vaccines. The induction of T-cell memory by free peptide immunization potentially has wide applicability in biology and medicine, including protection against infectious disease. | lld:pubmed |
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| pubmed-article:1848698 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1848698 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1848698 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1848698 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1848698 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:1848698 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:MeliefC JCJ | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:MeloenR HRH | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:KolakofskyDD | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:RouxLL | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:KastW MWM | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:BlomH JHJ | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:VoordouwA CAC | lld:pubmed |
| pubmed-article:1848698 | pubmed:author | pubmed-author:CurrenJJ | lld:pubmed |
| pubmed-article:1848698 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1848698 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:1848698 | pubmed:volume | 88 | lld:pubmed |
| pubmed-article:1848698 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1848698 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1848698 | pubmed:pagination | 2283-7 | lld:pubmed |
| pubmed-article:1848698 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1848698 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1848698 | pubmed:articleTitle | Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide. | lld:pubmed |
| pubmed-article:1848698 | pubmed:affiliation | Division of Immunology, The Netherlands Cancer Institute, Amsterdam. | lld:pubmed |
| pubmed-article:1848698 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1848698 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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