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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-3
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pubmed:dateCreated |
2008-11-25
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pubmed:abstractText |
There is a paucity of controlled clinical data on the best initial therapy for treating patients with bipolar type II (BP II) major depressive episode (MDE). In this analysis, we examined the safety and antidepressant efficacy of short-term venlafaxine versus lithium monotherapy in rapid and non-rapid cycling patients with BP II MDE. We hypothesized that lithium would have superior efficacy to venlafaxine, with fewer syndromal and sub-syndromal hypomanic and mixed mood conversions in the rapid cycling BP II MDE patients.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0165-0327
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-30
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pubmed:dateRevised |
2009-9-28
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pubmed:meshHeading |
pubmed-meshheading:18486235-Adolescent,
pubmed-meshheading:18486235-Adult,
pubmed-meshheading:18486235-Aged,
pubmed-meshheading:18486235-Antipsychotic Agents,
pubmed-meshheading:18486235-Bipolar Disorder,
pubmed-meshheading:18486235-Cyclohexanols,
pubmed-meshheading:18486235-Depressive Disorder, Major,
pubmed-meshheading:18486235-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:18486235-Drug Administration Schedule,
pubmed-meshheading:18486235-Female,
pubmed-meshheading:18486235-Humans,
pubmed-meshheading:18486235-Lithium Compounds,
pubmed-meshheading:18486235-Male,
pubmed-meshheading:18486235-Middle Aged,
pubmed-meshheading:18486235-Patient Dropouts,
pubmed-meshheading:18486235-Psychiatric Status Rating Scales,
pubmed-meshheading:18486235-Psychometrics,
pubmed-meshheading:18486235-Regression Analysis,
pubmed-meshheading:18486235-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Venlafaxine versus lithium monotherapy of rapid and non-rapid cycling patients with bipolar II major depressive episode: a randomized, parallel group, open-label trial.
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pubmed:affiliation |
Depression Research Unit, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, United States. jamsterd@mail.med.upenn.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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