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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-5-19
pubmed:abstractText
There are few reports showing the relationship between diabetes and the long-term outcome following percutaneous coronary intervention (PCI) in Asians. As well, the association between glycosylated hemoglobin (HbA1c) level and outcome remains controversial. In this analysis, 748 Japanese patients including 298 with diabetes (DM) and 450 without diabetes (non-DM) who underwent PCI from 1984 to 1992 were evaluated over the long term. The mean follow-up was 12.0 +/- 3.6 years. There were 47 (15.8%) total deaths in DM and 41 (9.1%) in non-DM [hazard ratio (HR) 1.71, 95% confidence interval (CI) 1.11-2.65, P = 0.013] and 28 (9.4%) cardiovascular deaths in DM and 19 (4.2%) in non-DM (HR 2.09, 95% CI 1.14-3.81, P = 0.016). Among DM, increased HbA1c was associated with both total (HR 1.25, 95% CI 1.03-1.53, P = 0.024) and cardiovascular (HR 1.30, 95% CI 1.00-1.69, P = 0.048) mortality. Even in Asians, DM showed an increased mortality following PCI. Among DM, increased HbA1c level was also associated with mortality.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0910-8327
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
149-54
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:18484156-Aged, pubmed-meshheading:18484156-Angioplasty, Balloon, Coronary, pubmed-meshheading:18484156-Asian Continental Ancestry Group, pubmed-meshheading:18484156-Biological Markers, pubmed-meshheading:18484156-Coronary Artery Disease, pubmed-meshheading:18484156-Diabetes Mellitus, Type 2, pubmed-meshheading:18484156-Female, pubmed-meshheading:18484156-Hemoglobin A, Glycosylated, pubmed-meshheading:18484156-Humans, pubmed-meshheading:18484156-Japan, pubmed-meshheading:18484156-Kaplan-Meier Estimate, pubmed-meshheading:18484156-Male, pubmed-meshheading:18484156-Middle Aged, pubmed-meshheading:18484156-Proportional Hazards Models, pubmed-meshheading:18484156-Retrospective Studies, pubmed-meshheading:18484156-Risk Assessment, pubmed-meshheading:18484156-Time Factors, pubmed-meshheading:18484156-Treatment Outcome
pubmed:year
2008
pubmed:articleTitle
Influence of diabetes on >10-year outcomes after percutaneous coronary intervention.
pubmed:affiliation
Department of Cardiology, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
pubmed:publicationType
Journal Article