rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1991-4-15
|
pubmed:abstractText |
Complementary DNA coding for a catalytic subunit of protein phosphatase 2B was isolated from a human teratocarcinoma library. It encodes a third isoform of protein phosphatase 2B beta, and differs from the cDNA for the second isoform by a deletion of 30 base pairs in the coding region. The deletion results in the loss of ten amino acids between the putative calmodulin site and a postulated autoinhibitory domain. An identical deletion occurs in one of the two alternatively spliced isoforms of PP2B alpha.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0006-3002
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
1088
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
308-10
|
pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1848109-Amino Acid Sequence,
pubmed-meshheading:1848109-Base Sequence,
pubmed-meshheading:1848109-Brain,
pubmed-meshheading:1848109-Calcineurin,
pubmed-meshheading:1848109-Calmodulin-Binding Proteins,
pubmed-meshheading:1848109-Cloning, Molecular,
pubmed-meshheading:1848109-DNA, Neoplasm,
pubmed-meshheading:1848109-Gene Library,
pubmed-meshheading:1848109-Humans,
pubmed-meshheading:1848109-Macromolecular Substances,
pubmed-meshheading:1848109-Molecular Sequence Data,
pubmed-meshheading:1848109-Oligonucleotide Probes,
pubmed-meshheading:1848109-Phosphoprotein Phosphatases,
pubmed-meshheading:1848109-RNA Splicing,
pubmed-meshheading:1848109-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1848109-Teratoma
|
pubmed:year |
1991
|
pubmed:articleTitle |
Identification of a third alternatively spliced cDNA encoding the catalytic subunit of protein phosphatase 2B beta.
|
pubmed:affiliation |
Department of Biochemistry, The University, Dundee, U.K.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|