Source:http://linkedlifedata.com/resource/pubmed/id/18475854
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2008-5-13
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| pubmed:abstractText |
Aiming at radiopharmaceutical application, (111)In(3+) complexes of the polyaminocarboxylates TTHA, TTHA-bis(butylamide) and TTHA-bis(glucamide) were investigated. The in vitro stability of (111)In(TTHA)(3-) and (111)In(TTHA-bis(butylamide)(-) was evaluated by measuring the exchange of (111)In(3+) from the complexes to transferrin and the results were compared with those for (111)In(DTPA)(2-). We also performed biodistribution studies of the three (111)In(3+) complexes by gamma-imaging in Wistar rats and by measuring the radioactivity in their organs. TTHA and its derivatives seem to have similar in vivo biodistribution with prevailing renal excretion.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:issn |
0793-0291
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
5
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
259-64
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| pubmed:year |
1998
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| pubmed:articleTitle |
In Vitro and In Vivo Behaviour of In Complexes of TTHA, TTHA-Bis(Butylamide) and TTHA-Bis(Glucamide): Stability, Biodistribution and Excretion Studied by Gamma Imaging.
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| pubmed:affiliation |
Serviço de Biofísica e Biomatemática Fac. Medicina Univ. de Coimbra Portugal.
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| pubmed:publicationType |
Journal Article
|