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rdf:type |
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lifeskim:mentions |
umls-concept:C0004927,
umls-concept:C0017262,
umls-concept:C0026336,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0038317,
umls-concept:C0086839,
umls-concept:C0205065,
umls-concept:C0205263,
umls-concept:C0392747,
umls-concept:C0871712,
umls-concept:C1555903
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pubmed:issue |
4
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pubmed:dateCreated |
2008-8-4
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pubmed:abstractText |
Postpartum depression (PPD) affects approximately 10% to 20% of women during the first 4 weeks of the postpartum period and is characterized by labile mood with prominent anxiety and irritability, insomnia, and depressive mood. During the postpartum period, elevated ovarian hormones abruptly decrease to the early follicular phase levels that are postulated to play a major role in triggering PPD. However, the underlying neurobiological mechanisms that contribute to PPD have not been determined.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1873-2402
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
311-9
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pubmed:meshHeading |
pubmed-meshheading:18471802-Analysis of Variance,
pubmed-meshheading:18471802-Animals,
pubmed-meshheading:18471802-Aquaporin 4,
pubmed-meshheading:18471802-Behavior, Animal,
pubmed-meshheading:18471802-Calcium-Calmodulin-Dependent Protein Kinase Type 2,
pubmed-meshheading:18471802-Depression, Postpartum,
pubmed-meshheading:18471802-Disease Models, Animal,
pubmed-meshheading:18471802-Estradiol,
pubmed-meshheading:18471802-Exploratory Behavior,
pubmed-meshheading:18471802-Female,
pubmed-meshheading:18471802-Gene Expression Regulation,
pubmed-meshheading:18471802-Helplessness, Learned,
pubmed-meshheading:18471802-Maze Learning,
pubmed-meshheading:18471802-Myogenic Regulatory Factors,
pubmed-meshheading:18471802-Nerve Tissue Proteins,
pubmed-meshheading:18471802-Ovariectomy,
pubmed-meshheading:18471802-Postpartum Period,
pubmed-meshheading:18471802-Rats,
pubmed-meshheading:18471802-Rats, Sprague-Dawley,
pubmed-meshheading:18471802-Receptors, GABA-A,
pubmed-meshheading:18471802-Steroids,
pubmed-meshheading:18471802-Swimming
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pubmed:year |
2008
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pubmed:articleTitle |
A postpartum model in rat: behavioral and gene expression changes induced by ovarian steroid deprivation.
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pubmed:affiliation |
Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, Connecticut 06508, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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