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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0017337,
umls-concept:C0024204,
umls-concept:C0026882,
umls-concept:C0027627,
umls-concept:C0030705,
umls-concept:C0238463,
umls-concept:C0812241,
umls-concept:C1155661,
umls-concept:C1512554,
umls-concept:C1704807
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pubmed:issue |
2
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pubmed:dateCreated |
2008-7-15
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pubmed:abstractText |
It remains to be investigated whether the aberrant methylation of DNA repair genes plays a pathogenic role in BRAF mutation-promoted tumorigenesis of papillary thyroid cancer (PTC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
247-55
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18470905-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:18470905-Adenosine,
pubmed-meshheading:18470905-Carcinoma, Papillary,
pubmed-meshheading:18470905-Cell Line, Tumor,
pubmed-meshheading:18470905-DNA Methylation,
pubmed-meshheading:18470905-DNA Mismatch Repair,
pubmed-meshheading:18470905-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18470905-Humans,
pubmed-meshheading:18470905-Lymphatic Metastasis,
pubmed-meshheading:18470905-MAP Kinase Signaling System,
pubmed-meshheading:18470905-Mutation,
pubmed-meshheading:18470905-Nuclear Proteins,
pubmed-meshheading:18470905-Proto-Oncogene Proteins B-raf,
pubmed-meshheading:18470905-Thymidine,
pubmed-meshheading:18470905-Thyroid Neoplasms
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pubmed:year |
2008
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pubmed:articleTitle |
Hypermethylation of the DNA mismatch repair gene hMLH1 and its association with lymph node metastasis and T1799A BRAF mutation in patients with papillary thyroid cancer.
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pubmed:affiliation |
Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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