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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1991-3-8
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pubmed:databankReference |
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pubmed:abstractText |
A 6.1-kilobase insertion into the rudimentary (r) gene was cloned and partially sequenced. The insertion consists of a 703-base-pair (bp) P element next to a 5.4-kilobase single-copy sequence. The normal position of the single-copy sequence is near the tip of the X chromosome. Upon insertion into the r gene, this chimeric element generated an 8-bp target-site duplication, characteristic of P elements. At the non-P-element end of the insertion, the first 8 bp are identical to the first 8 bp of the inverted terminal repeats of the P element. Thus, this element has inverted terminal repeats of 8 bp. This large element can excise from the r gene under conditions of hybrid dysgenesis, which indicates that it behaves like a normal P element. These data support the conclusion that a normally stable single-copy sequence has now become unstable and duplicated within the genome.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-1195397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-17246216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-17248751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-2545527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-271968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-3016507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-3021567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-6088058,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-6269753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-6295640,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-6295641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-6309410,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1846960-881736
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
693-7
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pubmed:dateRevised |
2010-9-10
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pubmed:meshHeading |
pubmed-meshheading:1846960-Animals,
pubmed-meshheading:1846960-Base Composition,
pubmed-meshheading:1846960-Base Sequence,
pubmed-meshheading:1846960-Blotting, Southern,
pubmed-meshheading:1846960-Cloning, Molecular,
pubmed-meshheading:1846960-Crosses, Genetic,
pubmed-meshheading:1846960-DNA,
pubmed-meshheading:1846960-DNA Transposable Elements,
pubmed-meshheading:1846960-Drosophila melanogaster,
pubmed-meshheading:1846960-Female,
pubmed-meshheading:1846960-Hybridization, Genetic,
pubmed-meshheading:1846960-Male,
pubmed-meshheading:1846960-Molecular Sequence Data,
pubmed-meshheading:1846960-Nucleic Acid Hybridization,
pubmed-meshheading:1846960-X Chromosome
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pubmed:year |
1991
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pubmed:articleTitle |
Capture of flanking DNA by a P element in Drosophila melanogaster: creation of a transposable element.
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pubmed:affiliation |
Department of Biology, University of Michigan, Ann Arbor 48109.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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