Linked Life Data

18469389

Source:http://linkedlifedata.com/resource/pubmed/id/18469389

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2008-5-12
pubmed:abstractText
In this study we applied bioassay using Chinese hamster ovary (CHO) cells with a heat shock protein (HSP) 47 promoter to the effluent of the wastewater treatment plants in Sapporo and we observed the statistically significant HSP production. This implied the effluent contained some organic matter which can stress the CHO cells. To investigate the possible causes of the toxicity of the effluent, we applied the assay to the rejected water from the sludge treatment plant, the mixtures of sewage and rejected water. The evolution of HSP production during the aerobic decay process and thickening process of sludge was also examined. These assay results showed that dissolved microbial products generated and/or released from activated sludge during its decay process in the aeration tank and during thickening and dewatering process in the sludge treatment train contributed to develop HSP production. The proteomics analysis was also applied to the effluent and detected the production of elongation factor 1beta. This result implies that the effluent from wastewater treatment plants may cause changes in cell proteins involved in allergic reaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0273-1223
pubmed:author
pubmed:copyrightInfo
(c) IWA Publishing 2008.
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1183-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Application of heat shock protein assay and proteome assay to water from wastewater treatment plant.
pubmed:affiliation
Department of Environmental Engineering, Hokkaido University, Kita 13, Nishi 8, Sapporo 060-8628, Japan. funamizu@eng.hokudai.ac.jp
pubmed:publicationType
Journal Article