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pubmed-article:18465804pubmed:abstractTextOsteosarcoma (OS) is a primary malignant tumor of the bone that typically presents in the second decade of life and has a poor prognosis, especially in metastatic cases. Wnt signaling contributes to the pathogenesis of tumors such as colon cancer and malignant melanoma. Wnt signaling controls normal bone formation during embryogenesis and homeostasis in adult organisms, thus we evaluated Wnt signaling in OS.lld:pubmed
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pubmed-article:18465804pubmed:articleTitleWnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival.lld:pubmed
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