rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-7-22
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pubmed:abstractText |
Osteosarcoma (OS) is a primary malignant tumor of the bone that typically presents in the second decade of life and has a poor prognosis, especially in metastatic cases. Wnt signaling contributes to the pathogenesis of tumors such as colon cancer and malignant melanoma. Wnt signaling controls normal bone formation during embryogenesis and homeostasis in adult organisms, thus we evaluated Wnt signaling in OS.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Frizzled Receptors,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/TCF Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/TCF7L2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tcf7l2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor 7-Like 2...,
http://linkedlifedata.com/resource/pubmed/chemical/WNT10B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt10b protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/beta Catenin
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1545-5017
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pubmed:author |
|
pubmed:copyrightInfo |
(c) 2008 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
349-55
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pubmed:dateRevised |
2011-6-1
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pubmed:meshHeading |
pubmed-meshheading:18465804-Animals,
pubmed-meshheading:18465804-Cell Communication,
pubmed-meshheading:18465804-Cell Line, Tumor,
pubmed-meshheading:18465804-Chemotaxis,
pubmed-meshheading:18465804-Frizzled Receptors,
pubmed-meshheading:18465804-Humans,
pubmed-meshheading:18465804-Mice,
pubmed-meshheading:18465804-Neoplasm Metastasis,
pubmed-meshheading:18465804-Osteosarcoma,
pubmed-meshheading:18465804-Proto-Oncogene Proteins,
pubmed-meshheading:18465804-Signal Transduction,
pubmed-meshheading:18465804-Survival Rate,
pubmed-meshheading:18465804-TCF Transcription Factors,
pubmed-meshheading:18465804-Transcription Factor 7-Like 2 Protein,
pubmed-meshheading:18465804-Wnt Proteins,
pubmed-meshheading:18465804-beta Catenin
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pubmed:year |
2008
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pubmed:articleTitle |
Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival.
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pubmed:affiliation |
Georgetown University School of Medicine, Washington, District of Columbia, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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