Source:http://linkedlifedata.com/resource/pubmed/id/18460327
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2008-5-7
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| pubmed:abstractText |
Type 3 deiodinase (D3) inactivates thyroid hormones. Simonides et al. (2008) now report that hypoxia-induced D3 activation leads to reduction of 3,5,3'-triiodothyronine (T3) and oxygen consumption, suggesting that D3 activation is a component of cellular responses to hypoxia and supporting the idea of cell-specific regulation of thyroid hormone levels by deiodinases.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
May
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| pubmed:issn |
1932-7420
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
363-4
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| pubmed:meshHeading |
pubmed-meshheading:18460327-Animals,
pubmed-meshheading:18460327-Anoxia,
pubmed-meshheading:18460327-Enzyme Activation,
pubmed-meshheading:18460327-Humans,
pubmed-meshheading:18460327-Hypoxia-Inducible Factor 1,
pubmed-meshheading:18460327-Iodide Peroxidase,
pubmed-meshheading:18460327-Signal Transduction,
pubmed-meshheading:18460327-Up-Regulation
|
| pubmed:year |
2008
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| pubmed:articleTitle |
Type 3 deiodinase in hypoxia: to cool or to kill?
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| pubmed:affiliation |
Department of Obstetrics, Gynecology & Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06510, USA. sabrina.diano@yale.edu
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| pubmed:publicationType |
Editorial
|