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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-2-12
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pubmed:abstractText |
Epidemiology and prognosis were analyzed in a consecutive, population-based series of 137 patients with malignant fibrous histiocytoma of soft tissue in the extremities and trunk wall, with a complete follow-up of minimum 3 years. All but one patient were treated by surgery in 28 cases combined with adjuvant radiotherapy or chemotherapy. The annual incidence was 0.42/10(5). The ratio men to women was 1.1. The median age was 64 years (range, 22 to 87 years). The thigh was the most common location. The median size was 6 cm. Superficial tumors constituted 43% and were smaller than deep-seated tumors. Eighty-three tumors were storiform-pleomorphic, 53 were myxoid, and one was of inflammatory type. The myxoid tumors were smaller and more often superficial. The cumulative 5-year survival rate for all patients was 0.7, but differed markedly between the histologic types; it was 1.0 in patients with myxoid tumors and 0.5 in patients with storiform-pleomorphic tumors. In the 77 patients with storiform-pleomorphic tumors without metastases at presentation, only tumor size larger than 10 cm and tumor necrosis independently impaired survival. The 23 patients who had none of these risk factors had a 5-year survival rate of 0.8.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
499-505
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1845950-Adult,
pubmed-meshheading:1845950-Aged,
pubmed-meshheading:1845950-Aged, 80 and over,
pubmed-meshheading:1845950-Combined Modality Therapy,
pubmed-meshheading:1845950-Female,
pubmed-meshheading:1845950-Follow-Up Studies,
pubmed-meshheading:1845950-Histiocytoma, Benign Fibrous,
pubmed-meshheading:1845950-Humans,
pubmed-meshheading:1845950-Incidence,
pubmed-meshheading:1845950-Lung Neoplasms,
pubmed-meshheading:1845950-Lymphatic Metastasis,
pubmed-meshheading:1845950-Male,
pubmed-meshheading:1845950-Middle Aged,
pubmed-meshheading:1845950-Multivariate Analysis,
pubmed-meshheading:1845950-Neoplasm Recurrence, Local,
pubmed-meshheading:1845950-Prognosis,
pubmed-meshheading:1845950-Soft Tissue Neoplasms,
pubmed-meshheading:1845950-Survival Rate,
pubmed-meshheading:1845950-Sweden
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pubmed:year |
1991
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pubmed:articleTitle |
Malignant fibrous histiocytoma of soft tissue. A population-based epidemiologic and prognostic study of 137 patients.
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pubmed:affiliation |
Department of Orthopedics, University Hospital, Lund, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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